The Gypsy Database (GyDB) of mobile genetic elements

The Gypsy Database (GyDB) of mobile genetic elements: release 2.0

In this article, we introduce the Gypsy Database (GyDB) of mobile genetic elements, an in-progress database devoted to the non-redundant analysis and evolutionary-based classification of mobile genetic elements. In this first version, we contemplate eukaryotic Ty3/Gypsy and Retroviridae long terminal repeats (LTR) retroelements. Phylogenetic analyses based on the gag-pro-pol internal region com...

Modelling the evolution of mobile genetic elements

The evolutionary implications of mobile genetic elements.

INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . The Evolutionary Hypotheses . .. . . . .. . . . .. . . ..... . . . . . . . . . ........ . . . .. . ....... . . .... . ... . .. . . . . General Considerations .. . . .............. . . . ....... ........ . ... . . ....

Mobile Genetic Elements of Nosocomial Pathogens

A significant increase in the isolation frequency of ciprofloxacin-resistant Escherichia coli was observed in the haematology departments of two university hospitals in The Netherlands. Amplified fragment length polymorphism analysis revealed that this increase was not caused by the emergence of unique ciprofloxacinresistant clones. Determination of the presence of class 1 integrons indicated t...

In this issue of Mobile Genetic Elements

Because transposons are able to self-excise and self-insert into the genome, they can also be used as a tool for altering gene expression, especially in the case of transposon mutagenesis. Here, Meredith et al. describe a robust transposon mutagenesis system that they have created allowing for the creation of a large range of expression genotypes in S. aureus. This collection has allowed for th...